TFTAK joins the Horizon Europe MSCA Doctoral Network FrameBio

TFTAK participates in the FrameBio project under Horizon Europe’s Marie Skłodowska-Curie Actions Doctoral Networks. The 36-month project runs from 2026 to 2029 and kicked off in Denmark, on January 23.

Pioneering Sustainable Biotech

FrameBio builds multiscale computational frameworks to simulate microbial behavior in bioproducts like Single Cell Proteins for food ingredience. These modules cover microorganism design, fermentation experiments with high-throughput screening, commercial production simulations, supply chain planning, and planetary resource impacts.

The network trains 13 doctoral candidates through joint research across academic, research, and industrial sites, blending synthetic biology, metabolic modeling, process engineering, and sustainability metrics to validate models up to pilot scale.​​

TFTAK Drives Optimization Advances

TFTAK contributes to Work Package 6 on multi-criteria decision models, experimental design, and automation integration. The team develops hybrid methods that combining multi-criteria decision-making, multi-objective optimisation, and a single-cell metabolic modelling (SCM) approach to improve SCP production efficiency, sustainability, and product quality.

TFTAK hosts a doctoral candidate focused on optimizing SCP sustainability, runs a workshop on multi-objective optimization, linear and non-linear programming, evolutionary algorithms (e.g., genetic algorithms), and tools such as MATLAB and R, and partners closely with Technische Universität Berlin and DTU in Denmark to link models with real-world decision-making using environmental, economic, and social key performance indicators.

FrameBio - Scaling BioSolutions for Global Impact

Ranno Nahku, R&D Director in Biotechnology at TFTAK: FrameBio is helping to turn sustainable biotechnology from promising concepts into scalable, data-driven industrial solutions. By combining advanced metabolic modelling, automation, and multi-objective optimisation, we can make smarter decisions that balance productivity, cost, and environmental impact from lab to pilot scale. For TFTAK, this collaboration strengthens our ability to accelerate the next generation of microbial production platforms, including Single Cell Proteins. Ultimately, it supports Europe’s role in building resilient and climate-smart bio-based value chains for global markets.

Global Partnership Network

FrameBio unites universities, research institutes, and businesses with expertise in bioprocess engineering and constraint-based modeling. TFTAK collaborates directly with Technische Universität Berlin and Technical University of Denmark (DTU), bridging modeling, automation, and decision support for global BioSolutions deployment.​​

The project FRAMEBIO - MULTISCALE FRAMEWORKS FOR BIOSOLUTIONS (No HORIZON-MSCA-2024-DN-01-01 (ID: 101227645)) is funded by Horizon Europe.